Appropriateness and affordability of prescriptions to diabetic patients attending a tertiary hospital in Eastern Uganda :

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dc.contributor.author Obakiro, Samuel Baker
dc.contributor.author Kiyimba, Kenedy
dc.contributor.author Napyo, Agnes
dc.contributor.author Kanyike, Andrew Marvin
dc.contributor.author Mayoka, Wilberforce John
dc.contributor.author Nnassozi, Aishah Ggalabuzi
dc.contributor.author Aguti, Beatrice
dc.contributor.author Akech, Gabriel Madut
dc.contributor.author Waako, John Paul
dc.date.accessioned 2021-05-04T13:07:49Z
dc.date.available 2021-05-04T13:07:49Z
dc.date.issued 2021-01-05
dc.identifier.citation Obakiro S. B., . . . et al. (2021) Appropriateness and affordability of prescriptions to diabetic patients attending a tertiary hospital in Eastern Uganda: A retrospective cross-sectional study. PLoS ONE 16(1): e0245036. https://doi.org/10.1371/journal.pone.0245036 en_US
dc.identifier.uri https://doi.org/10.60682/gjc4-p280
dc.description Article en_US
dc.description.abstract Irrational prescription of drugs can lead to high cost of treatment thus limiting access to essential medicines. We assessed the affordability and appropriateness of prescriptions written for diabetic patients in Eastern Uganda. Methods We collected secondary data from the health management information system registers of patients who attended the outpatient medical clinic at Mbale regional referral hospital from January 2019 to December 2019. The average cost of the prescriptions was calculated and adjusted odds ratios for predictors for unaffordability estimated using logistic regression. Computed scores for indicators of rational drug prescription were used to assess the extent of rational prescribing. Results The median cost per prescription was USD 11.34 (IQR 8.1, 20.2). Majority of the diabetic patients (n = 2462; 94.3%, 95% CI: 93.3–95.1%) could not afford the prescribed drugs. Predictors for unaffordability were if a prescription contained: 4 medicines (AOR = 12.45; 95% CI: 3.9–39.7); an injectable (AOR = 5.47; 95%CI: 1.47–20.32) and a diagnosis of diabetes mellitus with other comorbidities (AOR = 3.36; 95%CI: 1.95–5.78). Having no antidiabetic drug prescribed was protective for non-affordability (AOR = 0.38; 95%CI: 0.24–0.61). The average number of drugs per prescription was 2.8. The percentage prescription of drugs by generic name and from the essential medicine and health supplies list of Uganda were (6160/7461; 82.6%, 96% CI: 81.7%-83.4%) and (6092/7461; 81.7%, 95% CI: 80.8%-82.5%) respectively against WHO standard of 100%. Competing interests: The authors have declared Conclusion that no competing interests exist. The majority of diabetic patients (94.3%) in Eastern Uganda cannot afford to buy prescribed medicines. The government should therefore ensure that essential medicines are readily accessible in public health facilities. en_US
dc.description.sponsorship Busitema University en_US
dc.language.iso en en_US
dc.publisher Busitema University ; Plos One. en_US
dc.subject Prescriptions en_US
dc.subject Diabetic patients en_US
dc.subject Drugs en_US
dc.subject Treatment en_US
dc.subject Health management en_US
dc.subject Information system en_US
dc.subject Antidiabetic drug en_US
dc.title Appropriateness and affordability of prescriptions to diabetic patients attending a tertiary hospital in Eastern Uganda : en_US
dc.title.alternative a retrospective cross-sectional study en_US
dc.type Article en_US


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